Buffalo Bills vs. San Francisco 49ers Results

The following is a list of all regular season and postseason games played between the Buffalo Bills and San Francisco 49ers. The two teams have met each other 12 times, with the Buffalo Bills winning 6 games and the San Francisco 49ers winning 6 games.

Series tied 6-6-0

Date
Visitor
Home
Result
Box Score
10/16/16
SF
16
@
BUF
45
W
10/07/12
BUF
3
@
SF
45
L
11/30/08
SF
10
@
BUF
3
L
12/26/04
BUF
41
@
SF
7
W
12/02/01
BUF
0
@
SF
35
L
10/04/98
SF
21
@
BUF
26
W
12/03/95
BUF
17
@
SF
27
L
09/13/92
BUF
34
@
SF
31
W
12/17/89
BUF
10
@
SF
21
L
12/11/83
SF
23
@
BUF
10
L
12/21/80
BUF
18
@
SF
13
W
09/24/72
SF
20
@
BUF
27
W
 

Series tied 6-6-0
Points Scored: San Francisco 49ers 269, Buffalo Bills 234