| Player | Team | Att | Cmp | Pct | Yds | YPA | TD | TD% | Int | Int% | Lg | Sack | Loss | Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ken O'BrienK. O'Brien | NYJ | 488 | 297 | 60.9 | 3,888 | 8.0 | 25 | 5.1 | 8 | 1.6 | 96t | 62 | 399 | 96.2 |
| Boomer EsiasonB. Esiason | CIN | 431 | 251 | 58.2 | 3,443 | 8.0 | 27 | 6.3 | 12 | 2.8 | 68t | 32 | 289 | 93.2 |
| Joe MontanaJ. Montana | SF | 494 | 303 | 61.3 | 3,653 | 7.4 | 27 | 5.5 | 13 | 2.6 | 73 | 35 | 246 | 91.3 |
| Dan FoutsD. Fouts | SD | 430 | 254 | 59.1 | 3,638 | 8.5 | 27 | 6.3 | 20 | 4.7 | 75t | 18 | 135 | 88.1 |
| Dan MarinoD. Marino | MIA | 567 | 336 | 59.3 | 4,137 | 7.3 | 30 | 5.3 | 21 | 3.7 | 73 | 18 | 157 | 84.1 |
| Bill KenneyB. Kenney | KC | 338 | 181 | 53.6 | 2,536 | 7.5 | 17 | 5.0 | 9 | 2.7 | 84t | 28 | 223 | 83.6 |
| Jim McMahonJ. McMahon | CHI | 313 | 178 | 56.9 | 2,392 | 7.6 | 15 | 4.8 | 11 | 3.5 | 70t | 26 | 125 | 82.6 |
| Dieter BrockD. Brock | LA | 365 | 218 | 59.7 | 2,658 | 7.3 | 16 | 4.4 | 13 | 3.6 | 64t | 51 | 351 | 82.0 |
| Danny WhiteD. White | DAL | 450 | 267 | 59.3 | 3,157 | 7.0 | 21 | 4.7 | 17 | 3.8 | 56t | 30 | 257 | 80.6 |
| Neil LomaxN. Lomax | STL | 471 | 265 | 56.3 | 3,214 | 6.8 | 18 | 3.8 | 12 | 2.5 | 47 | 61 | 442 | 79.5 |
| Phil SimmsP. Simms | NYG | 495 | 275 | 55.6 | 3,829 | 7.7 | 22 | 4.4 | 20 | 4.0 | 70t | 52 | 396 | 78.6 |
| Dave KriegD. Krieg | SEA | 532 | 285 | 53.6 | 3,602 | 6.8 | 27 | 5.1 | 20 | 3.8 | 54 | 52 | 448 | 76.2 |
| Mark MaloneM. Malone | PIT | 233 | 117 | 50.2 | 1,428 | 6.1 | 13 | 5.6 | 7 | 3.0 | 45t | 10 | 80 | 75.5 |
| Eric HippleE. Hipple | DET | 406 | 223 | 54.9 | 2,952 | 7.3 | 17 | 4.2 | 18 | 4.4 | 56 | 49 | 343 | 73.6 |
| Steve DeBergS. DeBerg | TB | 370 | 197 | 53.2 | 2,488 | 6.7 | 19 | 5.1 | 18 | 4.9 | 57 | 19 | 143 | 71.3 |
| Lynn DickeyL. Dickey | GB | 314 | 172 | 54.8 | 2,206 | 7.0 | 15 | 4.8 | 17 | 5.4 | 63 | 30 | 226 | 70.4 |
| John ElwayJ. Elway | DEN | 605 | 327 | 54.0 | 3,891 | 6.4 | 22 | 3.6 | 23 | 3.8 | 65t | 38 | 307 | 70.2 |
| Ron JaworskiR. Jaworski | PHI | 484 | 255 | 52.7 | 3,450 | 7.1 | 17 | 3.5 | 20 | 4.1 | 99t | 34 | 289 | 70.2 |
| Bernie KosarB. Kosar | CLE | 248 | 124 | 50.0 | 1,578 | 6.4 | 8 | 3.2 | 7 | 2.8 | 68t | 19 | 121 | 69.3 |
| Warren MoonW. Moon | HOU | 377 | 200 | 53.1 | 2,709 | 7.2 | 15 | 4.0 | 19 | 5.0 | 80t | 46 | 366 | 68.5 |
| Tommy KramerT. Kramer | MIN | 506 | 277 | 54.7 | 3,522 | 7.0 | 19 | 3.8 | 26 | 5.1 | 57t | 39 | 255 | 67.8 |
| Tony EasonT. Eason | NE | 299 | 168 | 56.2 | 2,156 | 7.2 | 11 | 3.7 | 17 | 5.7 | 90t | 28 | 229 | 67.5 |
| Mike PagelM. Pagel | IND | 393 | 199 | 50.6 | 2,414 | 6.1 | 14 | 3.6 | 15 | 3.8 | 80t | 25 | 180 | 65.8 |
| Marc WilsonM. Wilson | LAR | 388 | 193 | 49.7 | 2,608 | 6.7 | 16 | 4.1 | 21 | 5.4 | 59 | 27 | 202 | 62.7 |
| Dave WilsonD. Wilson | NO | 293 | 145 | 49.5 | 1,843 | 6.3 | 11 | 3.8 | 15 | 5.1 | 50 | 39 | 291 | 60.7 |