| Player | Team | Gms | Att | Cmp | Pct | Yds | YPA | TD | TD%T% | Int | Int%I% | Lg | Sack | Loss | Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Matt RyanM. Ryan | ATL | 16 | 534 | 373 | 69.8 | 4,944 | 9.3 | 38 | 7.1 | 7 | 1.3 | 76t | 37 | 235 | 117.1 |
| Tom BradyT. Brady | NE | 12 | 432 | 291 | 67.4 | 3,554 | 8.2 | 28 | 6.5 | 2 | 0.5 | 79t | 15 | 87 | 112.2 |
| Dak PrescottD. Prescott | DAL | 16 | 459 | 311 | 67.8 | 3,667 | 8.0 | 23 | 5.0 | 4 | 0.9 | 83t | 25 | 143 | 104.9 |
| Aaron RodgersA. Rodgers | GB | 16 | 610 | 401 | 65.7 | 4,428 | 7.3 | 40 | 6.6 | 7 | 1.1 | 66t | 35 | 246 | 104.2 |
| Drew BreesD. Brees | NO | 16 | 673 | 471 | 70.0 | 5,208 | 7.7 | 37 | 5.5 | 15 | 2.2 | 98t | 27 | 184 | 101.7 |
| Sam BradfordS. Bradford | MIN | 15 | 552 | 395 | 71.6 | 3,877 | 7.0 | 20 | 3.6 | 5 | 0.9 | 71t | 37 | 276 | 99.3 |
| Kirk CousinsK. Cousins | WAS | 16 | 606 | 406 | 67.0 | 4,917 | 8.1 | 25 | 4.1 | 12 | 2.0 | 80t | 23 | 190 | 97.2 |
| Derek CarrD. Carr | OAK | 15 | 560 | 357 | 63.8 | 3,937 | 7.0 | 28 | 5.0 | 6 | 1.1 | 75t | 16 | 79 | 96.7 |
| Andrew LuckA. Luck | IND | 15 | 545 | 346 | 63.5 | 4,240 | 7.8 | 31 | 5.7 | 13 | 2.4 | 64t | 41 | 268 | 96.4 |
| Marcus MariotaM. Mariota | TEN | 15 | 451 | 276 | 61.2 | 3,426 | 7.6 | 26 | 5.8 | 9 | 2.0 | 60 | 23 | 156 | 95.6 |
| Ben RoethlisbergerB. Roethlisberger | PIT | 14 | 509 | 328 | 64.4 | 3,819 | 7.5 | 29 | 5.7 | 13 | 2.5 | 72t | 17 | 141 | 95.4 |
| Ryan TannehillR. Tannehill | MIA | 13 | 389 | 261 | 67.1 | 2,995 | 7.7 | 19 | 4.9 | 12 | 3.1 | 74t | 29 | 216 | 93.5 |
| Matthew StaffordM. Stafford | DET | 16 | 594 | 388 | 65.3 | 4,327 | 7.3 | 24 | 4.0 | 10 | 1.7 | 73t | 37 | 216 | 93.3 |
| Russell WilsonR. Wilson | SEA | 16 | 546 | 353 | 64.7 | 4,219 | 7.7 | 21 | 3.9 | 11 | 2.0 | 59 | 41 | 293 | 92.6 |
| Andy DaltonA. Dalton | CIN | 16 | 563 | 364 | 64.7 | 4,206 | 7.5 | 18 | 3.2 | 8 | 1.4 | 86t | 41 | 264 | 91.8 |
| Alex SmithA. Smith | KC | 15 | 489 | 328 | 67.1 | 3,502 | 7.2 | 15 | 3.1 | 8 | 1.6 | 80t | 28 | 140 | 91.2 |
| Colin KaepernickC. Kaepernick | SF | 12 | 331 | 196 | 59.2 | 2,241 | 6.8 | 16 | 4.8 | 4 | 1.2 | 65t | 36 | 207 | 90.7 |
| Tyrod TaylorT. Taylor | BUF | 15 | 436 | 269 | 61.7 | 3,023 | 6.9 | 17 | 3.9 | 6 | 1.4 | 84t | 42 | 192 | 89.7 |
| Philip RiversP. Rivers | SD | 16 | 578 | 349 | 60.4 | 4,386 | 7.6 | 33 | 5.7 | 21 | 3.6 | 59 | 36 | 188 | 87.9 |
| Carson PalmerC. Palmer | ARI | 15 | 597 | 364 | 61.0 | 4,233 | 7.1 | 26 | 4.4 | 14 | 2.4 | 80t | 40 | 281 | 87.2 |
| Jameis WinstonJ. Winston | TB | 16 | 567 | 345 | 60.9 | 4,090 | 7.2 | 28 | 4.9 | 18 | 3.2 | 45t | 35 | 239 | 86.1 |
| Eli ManningE. Manning | NYG | 16 | 598 | 377 | 63.0 | 4,027 | 6.7 | 26 | 4.3 | 16 | 2.7 | 75t | 21 | 142 | 86.0 |
| Trevor SiemianT. Siemian | DEN | 14 | 486 | 289 | 59.5 | 3,401 | 7.0 | 18 | 3.7 | 10 | 2.1 | 76t | 31 | 187 | 84.6 |
| Joe FlaccoJ. Flacco | BAL | 16 | 672 | 436 | 64.9 | 4,317 | 6.4 | 20 | 3.0 | 15 | 2.2 | 95t | 33 | 243 | 83.5 |
| Carson WentzC. Wentz | PHI | 16 | 607 | 379 | 62.4 | 3,782 | 6.2 | 16 | 2.6 | 14 | 2.3 | 73t | 33 | 213 | 79.3 |
| Blake BortlesB. Bortles | JAX | 16 | 625 | 368 | 58.9 | 3,905 | 6.2 | 23 | 3.7 | 16 | 2.6 | 51t | 34 | 197 | 78.8 |
| Case KeenumC. Keenum | LA | 10 | 322 | 196 | 60.9 | 2,201 | 6.8 | 9 | 2.8 | 11 | 3.4 | 65t | 23 | 140 | 76.4 |
| Cam NewtonC. Newton | CAR | 15 | 510 | 270 | 52.9 | 3,509 | 6.9 | 19 | 3.7 | 14 | 2.8 | 88t | 36 | 277 | 75.8 |
| Brock OsweilerB. Osweiler | HOU | 15 | 510 | 301 | 59.0 | 2,957 | 5.8 | 15 | 2.9 | 16 | 3.1 | 53 | 27 | 206 | 72.2 |
| Ryan FitzpatrickR. Fitzpatrick | NYJ | 14 | 403 | 228 | 56.6 | 2,710 | 6.7 | 12 | 3.0 | 17 | 4.2 | 57 | 19 | 81 | 69.6 |