St. Louis Rams Vs. San Francisco 49ers Results
Includes Regular Season and Postseason games.
| Date | Result | Attendance |
| 12/02/2012 | St. Louis Rams 16, San Francisco 49ers 13, OT | 57,279 |
| 11/11/2012 | San Francisco 49ers 24, St. Louis Rams 24 | 69,732 |
| 01/01/2012 | San Francisco 49ers 34, St. Louis Rams 27 | 55,990 |
| 12/04/2011 | San Francisco 49ers 26, St. Louis Rams 0 | 69,732 |
| 12/26/2010 | St. Louis Rams 25, San Francisco 49ers 17 | 52,820 |
| 11/14/2010 | San Francisco 49ers 23, St. Louis Rams 20, OT | 69,732 |
| 01/03/2010 | San Francisco 49ers 28, St. Louis Rams 6 | 47,965 |
| 10/04/2009 | San Francisco 49ers 35, St. Louis Rams 0 | 69,732 |
| 12/21/2008 | San Francisco 49ers 17, St. Louis Rams 16 | 54,948 |
| 11/16/2008 | San Francisco 49ers 35, St. Louis Rams 16 | 67,573 |
| 11/18/2007 | St. Louis Rams 13, San Francisco 49ers 9 | 68,039 |
| 09/16/2007 | San Francisco 49ers 17, St. Louis Rams 16 | 65,295 |
| 11/26/2006 | St. Louis Rams 20, San Francisco 49ers 17 | 65,517 |
| 09/17/2006 | San Francisco 49ers 20, St. Louis Rams 13 | 67,791 |
| 12/24/2005 | San Francisco 49ers 24, St. Louis Rams 20 | 65,473 |
| 09/11/2005 | San Francisco 49ers 28, St. Louis Rams 25 | 67,918 |
| 12/05/2004 | St. Louis Rams 16, San Francisco 49ers 6 | 65,793 |
| 10/03/2004 | St. Louis Rams 24, San Francisco 49ers 14 | 66,696 |
| 11/02/2003 | San Francisco 49ers 30, St. Louis Rams 10 | 67,812 |
| 09/14/2003 | St. Louis Rams 27, San Francisco 49ers 24, OT | 65,990 |
| 12/30/2002 | St. Louis Rams 31, San Francisco 49ers 20 | 66,118 |
| 10/06/2002 | San Francisco 49ers 37, St. Louis Rams 13 | 67,853 |
| 12/09/2001 | St. Louis Rams 27, San Francisco 49ers 14 | 66,218 |
| 09/23/2001 | St. Louis Rams 30, San Francisco 49ers 26 | 67,536 |
| 10/29/2000 | St. Louis Rams 34, San Francisco 49ers 24 | 68,109 |
| 09/17/2000 | St. Louis Rams 41, San Francisco 49ers 24 | 65,945 |
| 11/21/1999 | St. Louis Rams 23, San Francisco 49ers 7 | 68,193 |
| 10/10/1999 | St. Louis Rams 42, San Francisco 49ers 20 | 65,872 |
| 12/27/1998 | San Francisco 49ers 38, St. Louis Rams 19 | 68,386 |
| 10/25/1998 | San Francisco 49ers 28, St. Louis Rams 10 | 58,563 |
| 10/12/1997 | San Francisco 49ers 30, St. Louis Rams 10 | 63,825 |
| 09/07/1997 | San Francisco 49ers 15, St. Louis Rams 12 | 64,630 |
| 10/06/1996 | San Francisco 49ers 28, St. Louis Rams 11 | 61,260 |
| 09/08/1996 | San Francisco 49ers 34, St. Louis Rams 0 | 63,624 |
| 11/26/1995 | San Francisco 49ers 41, St. Louis Rams 13 | -- |
| 10/22/1995 | San Francisco 49ers 44, St. Louis Rams 10 | 59,915 |
| 11/20/1994 | San Francisco 49ers 31, Los Angeles Rams 27 | -- |
| 09/18/1994 | San Francisco 49ers 34, Los Angeles Rams 19 | -- |
| 11/28/1993 | San Francisco 49ers 35, Los Angeles Rams 10 | -- |
| 10/31/1993 | San Francisco 49ers 40, Los Angeles Rams 17 | -- |
| 11/22/1992 | San Francisco 49ers 27, Los Angeles Rams 10 | -- |
| 10/04/1992 | San Francisco 49ers 27, Los Angeles Rams 24 | -- |
| 11/25/1991 | San Francisco 49ers 33, Los Angeles Rams 10 | -- |
| 09/22/1991 | San Francisco 49ers 27, Los Angeles Rams 10 | -- |
| 12/17/1990 | San Francisco 49ers 26, Los Angeles Rams 10 | -- |
| 11/25/1990 | Los Angeles Rams 28, San Francisco 49ers 17 | -- |
| 01/14/1990 | San Francisco 49ers 30, Los Angeles Rams 3 (NFC Championship Game) | 65,634 |
| 12/11/1989 | San Francisco 49ers 30, Los Angeles Rams 27 | -- |
| 10/01/1989 | Los Angeles Rams 13, San Francisco 49ers 12 | -- |
| 12/18/1988 | Los Angeles Rams 38, San Francisco 49ers 16 | -- |
| 10/16/1988 | San Francisco 49ers 24, Los Angeles Rams 21 | -- |
| 12/27/1987 | San Francisco 49ers 48, Los Angeles Rams 0 | -- |
| 11/01/1987 | San Francisco 49ers 31, Los Angeles Rams 10 | -- |
| 12/19/1986 | San Francisco 49ers 24, Los Angeles Rams 14 | -- |
| 09/14/1986 | Los Angeles Rams 16, San Francisco 49ers 13 | -- |
| 12/09/1985 | Los Angeles Rams 27, San Francisco 49ers 20 | -- |
| 10/27/1985 | San Francisco 49ers 28, Los Angeles Rams 14 | -- |
| 12/14/1984 | San Francisco 49ers 19, Los Angeles Rams 16 | -- |
| 10/28/1984 | San Francisco 49ers 33, Los Angeles Rams 0 | -- |
| 10/23/1983 | San Francisco 49ers 45, Los Angeles Rams 35 | -- |
| 10/09/1983 | Los Angeles Rams 10, San Francisco 49ers 7 | -- |
| 01/02/1983 | Los Angeles Rams 21, San Francisco 49ers 20 | -- |
| 12/02/1982 | San Francisco 49ers 30, Los Angeles Rams 24 | -- |
| 11/22/1981 | San Francisco 49ers 33, Los Angeles Rams 31 | -- |
| 10/25/1981 | San Francisco 49ers 20, Los Angeles Rams 17 | -- |
| 10/19/1980 | Los Angeles Rams 31, San Francisco 49ers 17 | -- |
| 10/05/1980 | Los Angeles Rams 48, San Francisco 49ers 26 | -- |
| 11/25/1979 | Los Angeles Rams 26, San Francisco 49ers 20 | -- |
| 09/16/1979 | Los Angeles Rams 27, San Francisco 49ers 24 | -- |
| 11/19/1978 | Los Angeles Rams 31, San Francisco 49ers 28 | -- |
| 10/08/1978 | Los Angeles Rams 27, San Francisco 49ers 10 | -- |
| 11/20/1977 | Los Angeles Rams 23, San Francisco 49ers 10 | -- |
| 10/02/1977 | Los Angeles Rams 34, San Francisco 49ers 14 | -- |
| 11/21/1976 | Los Angeles Rams 23, San Francisco 49ers 3 | -- |
| 10/11/1976 | San Francisco 49ers 16, Los Angeles Rams 0 | -- |
| 11/09/1975 | San Francisco 49ers 24, Los Angeles Rams 23 | -- |
| 09/28/1975 | Los Angeles Rams 23, San Francisco 49ers 14 | -- |
| 11/04/1974 | Los Angeles Rams 15, San Francisco 49ers 13 | -- |
| 10/20/1974 | Los Angeles Rams 37, San Francisco 49ers 14 | -- |
| 11/18/1973 | Los Angeles Rams 31, San Francisco 49ers 13 | -- |
| 09/30/1973 | Los Angeles Rams 40, San Francisco 49ers 20 | -- |
| 12/04/1972 | Los Angeles Rams 26, San Francisco 49ers 16 | -- |
| 10/08/1972 | Los Angeles Rams 31, San Francisco 49ers 7 | -- |
| 11/21/1971 | Los Angeles Rams 17, San Francisco 49ers 6 | -- |
| 10/10/1971 | Los Angeles Rams 20, San Francisco 49ers 13 | -- |
| 11/29/1970 | Los Angeles Rams 30, San Francisco 49ers 13 | -- |
| 10/11/1970 | San Francisco 49ers 20, Los Angeles Rams 6 | -- |
| 11/09/1969 | Los Angeles Rams 41, San Francisco 49ers 30 | -- |
| 10/12/1969 | Los Angeles Rams 27, San Francisco 49ers 21 | -- |
| 11/17/1968 | San Francisco 49ers 20, Los Angeles Rams 20 | -- |
| 10/06/1968 | Los Angeles Rams 24, San Francisco 49ers 10 | -- |
| 11/05/1967 | Los Angeles Rams 17, San Francisco 49ers 7 | -- |
| 10/08/1967 | San Francisco 49ers 27, Los Angeles Rams 24 | -- |
| 11/06/1966 | San Francisco 49ers 21, Los Angeles Rams 13 | -- |
| 09/30/1966 | Los Angeles Rams 34, San Francisco 49ers 3 | -- |
| 11/21/1965 | San Francisco 49ers 30, Los Angeles Rams 27 | -- |
| 10/17/1965 | San Francisco 49ers 45, Los Angeles Rams 21 | -- |
| 12/06/1964 | San Francisco 49ers 28, Los Angeles Rams 7 | -- |
| 10/18/1964 | Los Angeles Rams 42, San Francisco 49ers 14 | -- |
| 12/01/1963 | Los Angeles Rams 21, San Francisco 49ers 17 | -- |
| 10/27/1963 | Los Angeles Rams 28, San Francisco 49ers 21 | -- |
| 11/18/1962 | San Francisco 49ers 24, Los Angeles Rams 17 | -- |
| 10/28/1962 | Los Angeles Rams 28, San Francisco 49ers 14 | -- |
| 11/12/1961 | Los Angeles Rams 17, San Francisco 49ers 7 | -- |
| 10/08/1961 | San Francisco 49ers 35, Los Angeles Rams 0 | -- |
| 12/04/1960 | San Francisco 49ers 23, Los Angeles Rams 7 | -- |
| 10/02/1960 | San Francisco 49ers 13, Los Angeles Rams 9 | -- |
| 11/08/1959 | San Francisco 49ers 24, Los Angeles Rams 16 | -- |
| 10/04/1959 | San Francisco 49ers 34, Los Angeles Rams 0 | -- |
| 11/09/1958 | Los Angeles Rams 56, San Francisco 49ers 7 | -- |
| 10/05/1958 | Los Angeles Rams 33, San Francisco 49ers 3 | -- |
| 11/10/1957 | Los Angeles Rams 37, San Francisco 49ers 24 | -- |
| 10/06/1957 | San Francisco 49ers 23, Los Angeles Rams 20 | -- |
| 11/11/1956 | Los Angeles Rams 30, San Francisco 49ers 6 | -- |
| 10/07/1956 | San Francisco 49ers 33, Los Angeles Rams 30 | -- |
| 11/06/1955 | Los Angeles Rams 27, San Francisco 49ers 14 | -- |
| 09/25/1955 | Los Angeles Rams 23, San Francisco 49ers 14 | -- |
| 11/07/1954 | Los Angeles Rams 42, San Francisco 49ers 34 | -- |
| 10/03/1954 | Los Angeles Rams 24, San Francisco 49ers 24 | -- |
| 11/08/1953 | San Francisco 49ers 31, Los Angeles Rams 27 | -- |
| 10/04/1953 | San Francisco 49ers 31, Los Angeles Rams 30 | -- |
| 11/30/1952 | Los Angeles Rams 34, San Francisco 49ers 21 | -- |
| 11/23/1952 | Los Angeles Rams 35, San Francisco 49ers 9 | -- |
| 11/04/1951 | Los Angeles Rams 23, San Francisco 49ers 16 | -- |
| 10/28/1951 | San Francisco 49ers 44, Los Angeles Rams 17 | -- |
| 11/05/1950 | Los Angeles Rams 28, San Francisco 49ers 21 | -- |
| 10/01/1950 | Los Angeles Rams 35, San Francisco 49ers 14 | -- |
Series tied 62-62-3
Points Scored: San Francisco 49ers 2829, St. Louis Rams 2722
