2008 Tennessee Titans Schedule & Results
| Regular Season |
| 09/07/2008 | Jacksonville Jaguars | W, 17-10 | 1-0-0 | 69,143 |
| 09/14/2008 | @ Cincinnati Bengals | W, 24-7 | 2-0-0 | 64,540 |
| 09/21/2008 | Houston Texans | W, 31-12 | 3-0-0 | 69,143 |
| 09/28/2008 | Minnesota Vikings | W, 30-17 | 4-0-0 | 69,143 |
| 10/05/2008 | @ Baltimore Ravens | W, 13-10 | 5-0-0 | 71,131 |
| 10/19/2008 | @ Kansas City Chiefs | W, 34-10 | 6-0-0 | 74,200 |
| 10/27/2008 (Mon.) | Indianapolis Colts | W, 31-21 | 7-0-0 | 69,143 |
| 11/02/2008 | Green Bay Packers | W, 19-16 OT | 8-0-0 | 69,143 |
| 11/09/2008 | @ Chicago Bears | W, 21-14 | 9-0-0 | 62,124 |
| 11/16/2008 | @ Jacksonville Jaguars | W, 24-14 | 10-0-0 | 65,258 |
| 11/23/2008 | New York Jets | L, 34-13 | 10-1-0 | 69,143 |
| 11/27/2008 (Thur.) | @ Detroit Lions | W, 47-10 | 11-1-0 | 60,112 |
| 12/07/2008 | Cleveland Browns | W, 28-9 | 12-1-0 | 69,143 |
| 12/14/2008 | @ Houston Texans | L, 13-12 | 12-2-0 | 70,831 |
| 12/21/2008 | Pittsburgh Steelers | W, 31-14 | 13-2-0 | 69,143 |
| 12/28/2008 | @ Indianapolis Colts | L, 23-0 | 13-3-0 | 66,721 |
