2010 NFL Draft
| Pick | Team | Player | Position | Birthdate | College |
| 1 | St. Louis Rams | Sam Bradford | QB | 11/08/1987 | Oklahoma |
| 2 | Detroit Lions | Ndamukong Suh | DT | 01/06/1987 | Nebraska |
| 3 | Tampa Bay Buccaneers | Gerald McCoy | DT | 02/25/1988 | Oklahoma |
| 4 | Washington Redskins | Trent Williams | OT | 07/19/1988 | Oklahoma |
| 5 | Kansas City Chiefs | Eric Berry | DB | 12/29/1988 | Tennessee |
| 6 | Seattle Seahawks | Russell Okung | OT | 10/07/1987 | Oklahoma State |
| 7 | Cleveland Browns | Joe Haden | DB | 04/14/1989 | Florida |
| 8 | Oakland Raiders | Rolando McClain | LB | 07/14/1988 | Alabama |
| 9 | Buffalo Bills | C.J. Spiller | RB | 08/15/1987 | Clemson |
| 10 | Jacksonville Jaguars | Tyson Alualu | DE | 05/12/1987 | California |
| 11 | San Francisco 49ers | Anthony Davis | OT | 10/11/1989 | Rutgers |
| 12 | San Diego Chargers | Ryan Mathews | RB | 05/01/1987 | Fresno State |
| 13 | Philadelphia Eagles | Brandon Graham | DE | 04/03/1988 | Michigan |
| 14 | Seattle Seahawks | Earl Thomas | DB | 05/07/1989 | Texas |
| 15 | New York Giants | Jason Pierre-Paul | DE | 02/28/1989 | South Florida |
| 16 | Tennessee Titans | Derrick Morgan | DE | 01/06/1989 | Georgia Tech |
| 17 | San Francisco 49ers | Mike Iupati | OG | 05/12/1987 | Idaho |
| 18 | Pittsburgh Steelers | Maurkice Pouncey | C | 07/24/1989 | Florida |
| 19 | Atlanta Falcons | Sean Weatherspoon | LB | 12/29/1987 | Missouri |
| 20 | Houston Texans | Kareem Jackson | DB | 04/10/1988 | Alabama |
| 21 | Cincinnati Bengals | Jermaine Gresham | TE | 06/16/1988 | Oklahoma State |
| 22 | Denver Broncos | Demaryius Thomas | WR | 12/25/1987 | Georgia Tech |
| 23 | Green Bay Packers | Bryan Bulaga | OT | 03/05/1989 | Iowa |
| 24 | Dallas Cowboys | Dez Bryant | WR | 11/04/1988 | Oklahoma State |
| 25 | Denver Broncos | Tim Tebow | QB | 08/14/1987 | Florida |
| 26 | Arizona Cardinals | Dan Williams | DT | 06/01/1987 | Tennessee |
| 27 | New England Patriots | Devin McCourty | DB | 08/13/1987 | Rutgers |
| 28 | Miami Dolphins | Jared Odrick | DT | 12/31/1987 | Penn State |
| 29 | New York Jets | Kyle Wilson | DB | 05/30/1987 | Boise State |
| 30 | Detroit Lions | Jahvid Best | RB | 01/30/1989 | California |
| 31 | Indianapolis Colts | Jerry Hughes | DE | 08/13/1988 | Texas Christian |
| 32 | New Orleans Saints | Patrick Robinson | DB | 09/07/1987 | Florida State |
Draft Results by Team
